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Other strategies that have been used to stabilize drug products in solution involve the use nonaqueous solvents such as mono- and polyhydric alcohols (eg, ethanol glycerin, and propyleneglycol) which can change the dielectric constant of the system Micellar solubilization by surfactants and reduction in solubility (as exempli ed by increase in the stability of penicillin in procaine penicillin in the presence of additives such as citrates, dextrose, sorbitol, and gluconate) are capable of reducing hydrolysis of drugs in solution [9] The in uence of packaging on the stability of drugs and drug products will be examined in greater detail later in this chapter, but suf ce it to state here that the permeability of the packaging materials to gases and liquids should be considered for all types of dosage forms since it can lead to decomposition of the drug products due to oxidation and hydrolysis.

A wireless network that does not include an access point is known as a computer-to-computer or adhoc network. Ad-hoc networks make wireless networking more flexible, in that they allow you to create a network between two or more computers without the need for an access point acting as an intermediary. If your wireless network includes an access point and is not moved between networks regularly, consider configuring the Access point (infrastructure) networks only option from the Preferred networks Advanced settings window. This option stops your computer from forming or attempting to connect to ad-hoc networks.

In the case of solution, leachables from container closure systems can alter the predetermined stability of liquid dosage forms For example, leaching of dioctyl phthalate, a plasticizer used in polyvinyl chloride (PVC) plastics, into intravenous solutions containing surfactants has been reported [11, 12] The potential adverse effect of the leached compound is twofold: on the safety of the patient and on the stability of the drug administered intravenously Under the consideration for the suitability for the intended use of any proposed packaging system, as indicated by the US Food and Drug Administration (FDA), compatibility (packaging components are regarded compatible with the dosage form if there is no suf cient interaction to cause unacceptable changes in the quality of either the dosage form or the packaging component, ie.

35 times that of the antenna with a driven patch only (about 2%) The parasitic patches can be stacked on top of the microstrip antenna [53, 54] and signi cant bandwidth enhancement can be achieved Decreasing the quality factor of the microstrip antenna is also an effective way of increasing the antenna s impedance bandwidth This kind of bandwidth-enhancement technique includes the use of a thick air or foam substrate [55 65] and the loading of a chip resistor on a microstrip antenna with a thin dielectric substrate [26, 66] In the former case, for feeding using a probe feed, a large reactance owing to the long probe pin in the thick substrate layer is usually a problem in achieving good impedance matching over a wide frequency range.

, leachable-induced degradation, precipitation, or changes in pH) and safety (packaging components should be constructed of materials that will not leach harmful or undesirable amounts of substances.

synchronization is handled by the secondary server. The secondary server will query the primary periodically to see if there are any updates and, if so, will perform the update to its record. 9 The authority for the level can assign almost anything that he wants. Normally the name would re ect some identi cation that re ects the users it serves. The name must be 63 characters or less; other than that, the sky is the limit.

To overcome this problem associated with probe-fed microstrip antennas, designs have been reported that embed a U-shaped slot in the patch (U-slotted patch) [55, 56], use a three-dimensional (3D) microstrip transition feed [57], cut a pair of wide slits at one of the patch s radiating edges.

2. Compose the e-mail message as you normally would, complete with the recipient s e-mail address and a suitable subject line. 3. In the message window, click Tools Digitally Sign, as shown in Figure 11-17. The read seal icon is added to the upper-right corner of the message window.